15-night Grand Heartland Cruise

September 26, 2025

American Cruise Lines: American Serenade

St. Paul/New Orleans

Vacation Offer ID 1560731

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The Signature Collection – Exclusive Amenities
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Cruise Inclusions

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Destination Guide
Suggested Shore Excursions

Destination	Arrival	Departure
St. Paul St. Paul 09/26/2025 The Twin Cities offer world-class art galleries, museums, and live performances. St. Paul’s Summit Avenue showcases gorgeous historic mansions built in the late 1800s. The enormous Mall of America includes more than 500 stores and an indoor waterpark and theme park. View gorgeous panoramas of the city from Mounds Park and cherish the enchantment of Minnehaha Falls with its 53-foot cascade. Settle into your hotel and enjoy the city at your leisure.	09/26/2025	09/26/2025
Mississippi River Cruising Mississippi River Cruising 09/27/2025 Board your ship and be treated to a Welcome Reception. Get to know your fellow guests and savor the view as you set out cruising Mark Twain’s river. Admire the breathtaking scenery that has inspired the country’s most legendary writers, artists, and musicians.	09/27/2025	09/27/2025
La Crosse La Crosse 09/28/2025 Step into 19th-century America in La Crosse, located on the banks of three captivating rivers. La Crosse is home to Riverside Park, where you’ll discover beautiful gardens, an outdoor performance center, and inspiring sculptures. Enjoy breathtaking, panoramic views from Grand Dad’s Bluff, a 600-ft high bluff which overlooks the entire city. Led by a local expert, gain insight into the city’s development from the boomtown riverboat days through the roaring ‘20s to the challenges and opportunities of the 21st century.	09/28/2025	09/28/2025
Dubuque Dubuque 09/29/2025 A “Masterpiece on the Mississippi,” Dubuque is among the oldest settlements west of the river. Take a ride on the Fenelon Place Elevator, the world’s shortest and steepest scenic railway, or try your luck in one of Dubuque's state-of-the-art casinos. View colorful Victorian mansions, stroll through the bustling downtown area, or visit the national Mississippi River Museum and Aquarium.	09/29/2025	09/29/2025
Davenport Davenport 09/30/2025 Voted one of the Most Livable Small Cities in America, Davenport is often described as a lively, active city with a hometown feel. The Legacy of John Deere, the largest agricultural exhibit in the world, resides here. Music enthusiasts will enjoy Davenport’s many festivals, including the Mississippi Valley Blues Festival, The Mississippi Valley Fair, and the Bix Beiderbecke Memorial Jazz Festival.	09/30/2025	09/30/2025
Mississippi River Cruising Mississippi River Cruising 10/01/2025 Admire the beautiful countryside adorned with rolling hills and steep bluffs. Along the way we will traverse a several locks and dams, a magnificent feat of human engineering. Enjoy watching the river commerce, including towboats and moving commodities including grains, petroleum products, and coal.	10/01/2025	10/01/2025
Hannibal Hannibal 10/02/2025 Hannibal, “America’s Hometown,” is a place where you can rediscover adventures from Mark Twain’s era. Tom Sawyer and Huck Finn come to life in this charming Missouri town, where you can run your hand along Aunt Polly’s fence, explore Injun Joe’s Cave, and get reacquainted with one of the world’s most beloved authors. The downtown area is a thriving haven for artisans, filled with specialty shops unique to Hannibal.	10/02/2025	10/02/2025
Mississippi River Cruising Mississippi River Cruising 10/03/2025 As you make your way from Hannibal to St. Louis, reflect upon the rich history of the Mississippi River and the variety of music born upon its shores. Listen to the talented performers in one of our lounges or share the afternoon with fellow travelers.	10/03/2025	10/03/2025
St. Louis St. Louis 10/04/2025 St. Louis is often referred to as the “Gateway to the West.” Take in the Gateway Arch Riverfront, highlighted by the Gateway Arch, the largest man-made monument in the U.S. Enjoy St. Louis' many world-class attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum. End your day by relaxing at the Missouri Botanical Garden, one of the world’s most popular public gardens.	10/04/2025	10/04/2025
Memphis Memphis 10/05/2025 Welcome to Memphis, a historic city which rises picturesquely up the hillside from the river, adorned with grand oak trees, lush parks, and historic sites that commemorate everything from the Civil War to the Civil Rights Movement. Immerse yourself in its rich musical legacy as you stroll along legendary Beale Street, where music flows from every doorway, and savor the rich flavors and aromas of the city’s famous BBQ.	10/05/2025	10/05/2025
Tunica Tunica 10/06/2025 Times have changed, but not in Downtown Tunica, with Main Street buildings just as they were at the turn of the century. Explore unique boutiques, antique shops, a fully restored courthouse, and Tunica Veterans Memorial at Rivergate Park. Here, you can enjoy the kind of southern hospitality you thought only existed in storybooks.	10/06/2025	10/06/2025
Mississippi River Cruising Mississippi River Cruising 10/07/2025 As you cruise toward the historic city of Vicksburg, enjoy the beauty of the heart and soul of the Mississippi Delta. Mingle with guests in one of our comfortable, read a good book on your private balcony, or take part in one of our many onboard activities.	10/07/2025	10/07/2025
Vicksburg Vicksburg 10/08/2025 Vicksburg is a place of drama. During the Civil War, the struggle to control Vicksburg proved to be a major turning point. The well-fortified connection between river and rail transportation was known as “The Gibraltar of the West.” A narrated exploration of the well-preserved National Military Park battlefield enlivens this powerful story and highlights its significance.	10/08/2025	10/08/2025
Natchez Natchez 10/09/2025 In Natchez, grand homes sparkle like jewels, adorning the bluffs that tower above the river. Since 1716, when the French first built a fort here among the Natchez Indians, the town has grown to boast elaborate mansions built by planters in the 1800s to flaunt their wealth.	10/09/2025	10/09/2025
Baton Rouge Baton Rouge 10/10/2025 Meaning “red stick,” Baton Rouge’s 1699 French name references an ancient geographical marker and reflects the city’s long history. As Louisiana’s state capital, the city still echoes with tales of the characters who lived here, most notably Governor and Senator Huey P. Long. Learn about his dramatic career at the magnificent 1852 Old State Capitol Museum and visit Long’s 1932 State Capitol building, an architectural marvel of granite and marble.	10/10/2025	10/10/2025
New Orleans New Orleans 10/11/2025 New Orleans is worth some extra time. Enjoy a feast for your senses if you linger in this magical city, renowned for its delicious cuisine, vibrant music scene, and rich culture with an international flair. Stroll the tree-lined avenues, take a carriage ride through the French Quarter, hop aboard a streetcar to the gorgeous Garden District, or visit the renowned National World War II Museum. If departing the ship in New Orleans, enjoy available city excursions and motorcoach transfers to the airport. Or extend your stay to further explore the delights of the Big Easy.	10/11/2025	10/11/2025

American Cruise Lines: American Serenade

American Serenade won Cruise Critic’s Editors’ Picks Award for Best New River Cruise Ship of the Year recently, the first time an American ship has received this prestigious award. Introduces an updated modern interior design, integrating an elegant and refined aesthetic with tradition for the spacious comfort found aboard all of ships Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.

Ship Statistics

Maiden Voyage: 2023
Passenger Capacity: 175
Number of Staterooms: 91

Number of Suites: 16
Wheelchair Accessible: Yes

Suite

Veranda Suite (Private Balcony) (VS) Call for pricing

Category: VS
Deck 4

With a generous 405 sq. ft. of relaxing space, each Veranda suite includes a private walk-out balcony to enjoy the panoramic views. Considered one of the finest staterooms on any cruise ship, guests will enjoy full-size bathrooms and large living area with sliding glass door.

Grand Suite (Private Balcony) (GS) Call for pricing

Category: GS
Deck 4

The luxurious Grand Suite measures 650 sq. ft. and offers panoramic views through floor-to-ceiling glass windows. Sliding glass doors lead out to a private balcony complete with a private dining area, the perfect place to enjoy breakfast room service or watch the sun set. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration.

Balcony

Single (Private Balcony) (SGB) Call for pricing

Category: SGB
Deck 4
Deck 3
Deck 2

Perfect for the solo traveler, the Single staterooms offer all of the amenities you expect from a fine hotel. At 250 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.

Balcony Stateroom (AAR) Call for pricing

Category: AAR
Deck 1

AAR staterooms on the main deck offer complete comfort with approximately 275 sq. ft. of living space. Enjoy a full-size bathroom, large picture window, and door leading out to a furnished private balcony. These staterooms also feature a large sitting area, ideal for getting together with friends.

Balcony Stateroom (AAM) Call for pricing

Category: AAM
Deck 3

Located on the third deck, these spacious staterooms feature commanding views of the passing river landscapes. At 350 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor-to-ceiling sliding glass doors with a private balcony to offer panoramic views from every angle.

Balcony Stateroom (AAC) Call for pricing

Category: AAC
Deck 2

AAC staterooms are conveniently located on the second deck and offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular views of the surrounding landscape. At 316 sq. ft., these staterooms also offer a sitting area, desk and full-size bathrooms.

Prices are per person based on double occupancy. Pricing on some sailings may reflect special limited time offers, not combinable with any other offers/discounts. Valid on new bookings only. American Cruise Lines includes all shipboard meals, entertainment, tips and gratuities, alcohol, and other port charges and fees in the price of the cruise. Many shore excursions are also included in the cost of the cruise.

All fares are quoted in US Dollars.

Deck 5