8-night Upper Mississippi River
8-night Upper Mississippi River
October 10, 2025
American Cruise Lines:
American Melody
St. Louis (Alton)/St. Paul
Vacation Offer ID 1506909
Reference this number when contacting our travel specialist.
Cruise Theme: Mark Twain Cruise
Explore the Mississippi's Literary History, with a Stop at Hannibal, MO. Few American authors are as beloved as Samuel Clemens, better known by his pen name, Mark Twain. On this special theme cruise, explore the river that served as his inspiration, complete with a true-to-life Mark Twain impersonator, and a stop in Hannibal, MO, Twain's hometown.
The Signature Collection – Exclusive Amenities
The Signature Collection Sailings offer Exceptional Value and Exclusive Amenities.
The Signature Collection Sailings offer Exceptional Value and Exclusive Amenities.
Cruise Inclusions
- Cruise
- Meals
- Entertainment and more
- Destination Guide
- Suggested Shore Excursions
Destination | Arrival | Departure |
---|---|---|
St. Louis (Alton)
|
10/10/2025 | 10/10/2025 |
Mississippi River Cruising
|
10/11/2025 | 10/11/2025 |
Hannibal | 10/12/2025 | 10/12/2025 |
Fort Madison
|
10/13/2025 | 10/13/2025 |
Davenport | 10/14/2025 | 10/14/2025 |
Dubuque | 10/15/2025 | 10/15/2025 |
Winona
|
10/16/2025 | 10/16/2025 |
Red Wing | 10/17/2025 | 10/17/2025 |
St. Paul
|
10/18/2025 | 10/18/2025 |
The Future of American River Cruising™ continues with American Melody, the 4th in the modern riverboat series. American Melody showcases a whole new aesthetic, with an updated interior design, bringing ship to the next level of modern sophistication. Specifically designed to navigate the Mississippi River, American Melody features panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms feature full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. American Melody also offers the Ellipse Café for casual dining, an option that has been very popular with the guests.
Dining
Bar & Lounges
Onboard Activities
Outdoor Activities
Wellness
Suite
Balcony
Fares listed are per person, based on double occupancy and include all gratuities, port charges and fees.
Prices are per person based on double occupancy. Pricing on some sailings may reflect special limited time offers, not combinable with any other offers/discounts. Valid on new bookings only. American Cruise Lines includes all shipboard meals, entertainment, tips and gratuities, alcohol, and other port charges and fees in the price of the cruise. Many shore excursions are also included in the cost of the cruise.
All fares are quoted in US Dollars.